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Friday, November 1, 2013

Classification of Antibiotics, Kinds, Types, List, Uses, Benefits, Side Effects


Classification of Antibiotics, Kinds, Types, List, Uses, Benefits, Side Effects 

- The following is a list, all kinds, types, or classes of antibiotics, sorted by class. Highest division is between bactericidal antibiotics and bacteriostatic antibiotics. Bactericidal kill bacteria directly while bacteriostatic prevent bacteria to cell division or reproduction. However, this classification is only based on the results of laboratory research. In practice, both the bactericidal and bacteriostatic antibiotics to overcome bacterial infections.
http://en.wikipedia.org/wiki/List_of_antibiotics
Mechanism of Action / How it Works
1 . Aminogliserida
amikacin
Amikin
To cope with infections caused by gram-negative bacteria such as Escherichia coli and Klebsiella , and Pseudomonas aeruginosa main . Effective against anaerobic bacteria ( facultative anaerobes ) and tularemia .
hearing loss
vertigo
kidney damage
Binds to the 30S ribosomal subunit of bacteria ( some of which bind to the 50S ribosomal subunit ) , inhibiting the translocation of peptidyl - tRNA from the A -site to P -site and also cause reading errors RNA , so that bacteria can not synthesize proteins vital to its growth .
gentamicin
Garamycin
kanamycin
Kantrex
neomycin
Neo - Fradin [ 3 ]
netilmicin
Netromycin
tobramycin
Nebcin
paromomycin
Humatin
spectinomycin
Trobicin
Gonorrhoea ( gonorrhea )

Prevent cell division by inhibiting bacterial cell wall synthesis .
2 . Ansamisin
geldanamycin
Antitumor antibiotics ( still under investigation )

Herbimycin

Rifaximin , streptomycin
XIFAXAN
Traveler's diarrhea ( diarrhea caused by long trips / tours ) caused by E. coli .

3 . Carbacephem
loracarbef
Lorabid
The use of antibiotics is not continued .


carbapenem
Ertapenem
Invanz
As bactericidal ( kills bacteria ) to gram positive and negative bacteria , therefore very useful to address the broad spectrum of bacteria .
Indigestion and diarrhea
nausea
convulsions
headache
Rashes and allergic reactions

doripenem
Doribax

Imipenem / cilastatin
Primaxin

meropenem
Merrem

4 . Cephalosporin ( first generation )
Cefadroxil
Duricef
Very effective to treat infections caused by gram-positive bacteria
Indigestion and diarrhea
Nausea ( if taken together with alcohol )
allergic reactions
Its mechanism of action is similar to beta - lactam antibiotics ( inhibits bacterial cell wall biosynthesis ) that is by disrupting the synthesis of peptidoglycan in bacterial cell wall layer .
cefazolin
Ancef
Cefalotin or Cefalothin
Keflin ( its use was discontinued )
Cefalexin
Keflex
5 . Cephalosporin ( second generation )
cefaclor
Distaclor
Against gram-positive bacteria ( narrow scope ) and gram negative ( wide scope )
Indigestion and diarrhea
Nausea ( if taken together with alcohol )
allergic reactions
Its mechanism of action is similar to beta - lactam antibiotics ( inhibits bacterial cell wall biosynthesis ) that is by disrupting the synthesis of peptidoglycan in bacterial cell wall layer .
Cefamandole
Mandol ( its use was discontinued )
cefoxitin
Mefoxin ( its use was discontinued )
Cefprozil
Cefzil
cefuroxime
Ceftin , Zinnat ( UK )
6 . Cephalosporin ( third generation )
cefixime
Suprax
Against gram-positive bacteria ( narrow scope ) and gram negative ( broad scope ) except Pseudomonas .
Indigestion and diarrhea
Nausea ( if taken together with alcohol )
allergic reactions
Its mechanism of action is similar to beta - lactam antibiotics ( inhibits bacterial cell wall biosynthesis ) that is by disrupting the synthesis of peptidoglycan in bacterial cell wall layer .
cefdinir
Omnicef ​​, Cefdiel
Cefditoren
Spectracef
cefoperazone
Cefobid ( its use was discontinued )
cefotaxime
Claforan
cefpodoxime
Vantin
ceftazidime
Fortaz
ceftibuten
Cedax
Ceftizoxime
Cefizox ( its use was discontinued )
ceftriaxone
Rocephin
7 . Cephalosporin ( fourth generation )
Cefepime
Maxipime
Treat infections caused by Pseudomonas bacteria .
Indigestion and diarrhea
Nausea ( if taken together with alcohol )
allergic reactions
Its mechanism of action is similar to beta - lactam antibiotics ( inhibits bacterial cell wall biosynthesis ) that is by disrupting the synthesis of peptidoglycan in bacterial cell wall layer .
8 . Cephalosporin ( fifth generation )
ceftaroline fosamil
Teflaro
To overcome MRSA ( Methicillin - resistant Staphylococcus aureus )
Indigestion and diarrhea
allergic reactions
Its mechanism of action is similar to beta - lactam antibiotics ( inhibits bacterial cell wall biosynthesis ) that is by disrupting the synthesis of peptidoglycan in bacterial cell wall layer .
ceftobiprole
Zeftera
To overcome MRSA ( Methicillin - resistant Staphylococcus aureus )
Indigestion and diarrhea
Nausea ( if taken together with alcohol )
allergic reactions
9 . glycopeptides
teicoplanin
Targocid ( UK )
Active against Gram positive aerobic and anaerobic including MRSA , Vancomycin is used orally for the treatment of infections caused by Clostridium difficile

Inhibits the synthesis of peptidoglycan
vancomycin
Vancocin
Telavancin
Vibativ
10 . Linkosamida
clindamycin
Cleocin
Overcome the acute infection caused by Staphylococcus aureus , pneumonia ( lung inflammation ) , infection caused by streptococcus bacteria in patients who are allergic to penicillin , infections caused by anaerobic bacteria . Clindamycin can be used to treat acne .
pseudomembranous enterocolitis ( inflammation of the large intestine / colon )
Binding subunit 50S rRNA thereby inhibiting bacterial protein synthesis .
lincomycin
Lincocin
11 . lipopeptide
daptomycin
Cubicin
Treat infections caused by gram-positive bacteria .

Bind to the membrane so that the rapid depolarization . This causes the membrane potential ( change in electrical potential between the inside and outside of the cell ) to trigger the synthesis of RNA , DNA , and protein .
12 . macrolides
azithromycin
Zithromax , Sumamed , Xithrone
Treat infections caused by Staphylococcus , syphilis , upper respiratory tract infection ( ARI ) , lower respiratory tract infections , infections caused by mycoplasma , Lyme disease ( an infectious disease caused by at least three species of bacteria belonging to the genus Borrelia )


clarithromycin
Biaxin


dirithromycin
Dynabac


erythromycin
Erythocin , Erythroped


roxithromycin



troleandomycin
Tao
Nausea , vomiting , and diarrhea ( especially at higher doses ) ,
QT interval be long / long ( especially erythromycin ) . QT syndrome is a disorder of the heart elektrin system so that the heart beats faster .
jaundice
Inhibits bacterial protein biosynthesis by binding to the 50S subunit of bacterial ribosomes thereby inhibiting translocation of peptidyl tRNA .
telithromycin
monkey
Overcoming Pneumonia
Visual disturbances , liver toxicity . [ 4 ]
Spiramycin
Rovamycine
Infections in the mouth .

13 . Monobactam
aztreonam
Azactam


Its mechanism of action is similar to beta - lactam antibiotics ( inhibits bacterial cell wall biosynthesis ) that is by disrupting the synthesis of peptidoglycan in bacterial cell wall layer .
14 . Nitrofuran
furazolidone
Furoxone
Addressing diarrhea or enteritis ( inflammation of the small intestine ) caused by bacteria or protozoa .


nitrofurantoin
Macrodantin , Macrobid
Urinary tract infection


15 . Oxazolidonona
linezolid
Zyvox



Posizolid
Phase II clinical trials
Treat infections caused by Staphylococcus aureus are resistant to Vancomycin
Thrombocytopenia ( decreased number of blood keeping )
Peripheral neuropathy ( damage to nerve cells in the peripheral nervous system )

Inhibits protein synthesis by inhibiting the initiation stage .
Radezolid
Phase II clinical trials

torezolid
Phase II clinical trials

16 . penicillin
amoxicillin
Novamox , Amoxil
Overcome various kinds of infections . Penicillin is used to treat streptococcal infections , syphilis and Lyme disease .

Indigestion and diarrhea
Allergy followed by an acute anaphylactic reaction . Anaphylaxis is an allergic reaction that occurs rapidly and can cause death .
Brain and kidney damage ( rare )
Its mechanism of action is similar to beta - lactam antibiotics ( inhibits bacterial cell wall biosynthesis ) that is by disrupting the synthesis of peptidoglycan in bacterial cell wall layer .
ampicillin
Principen ( its use was discontinued )
Azlocillin

carbenicillin
Geocillin ( its use was discontinued )
cloxacillin
Tegopen ( its use was discontinued )
dicloxacillin
Dynapen ( its use was discontinued )
flucloxacillin
Floxapen ( patent sale to Actavis Group Europe ) . Actavis is a generic drug company that develops and centered in the United States .
Mezlocillin
Mezlin ( its use was discontinued )
methicillin
Staphcillin ( its use was discontinued )
nafcillin
Unipen ( its use was discontinued )
oxacillin
Prostaphlin ( its use was discontinued )
penicillin G
Pentids ( its use was discontinued )
penicillin V
Veetids ( Pen - Vee - K ) ( its use was discontinued )
Piperacillin
Pipracil ( its use was discontinued )
Penicillin G potassium
Pfizerpen ( its use was discontinued )
Temocillin
Negaban ( UK ) ( its use was discontinued )
Ticarcillin
Ticar ( its use was discontinued )



17 . combination Penicillin
Amoxicillin / clavulanate
Augmentin


The second compound to prevent bacteria resistant to the main compound .
Ampicillin / sulbactam
Unasyn


Piperacillin / tazobactam
Zosyn


Ticarcillin / clavulanate
Timentin


18 . polypeptide
Bacitracin

Treat infections of the eye , ear and bladder . The use of antibiotics is usually directly applied to the eyes or inhaled through the nose to the lungs and rarely by injection even though the need for applications to the blood vessels is needed due to rampant organisms MDR ( multi drugs resistance ) .
Kidney and nerve damage ( when given by injection )
Inhibit isoprenyl pyrophosphate , a molecule that carries compounds builders ( building block ) of peptidoglycan on the outer side of the inner membrane of the bacterial cell wall [ 5 ]
Interact with the cytoplasmic membrane and the outer side of the cell membrane of bacteria . This triggers the change of ion . Antibiotics will act like a detergent molecule in the membrane permeability change . Polymyxin B and E function as a bactericide , although the isosmotic solution ( equal osmotic pressure )
colistin
Coly - Mycin - S
Polymyxin B

19 . Kuinolona
ciprofloxacin
Cipro , Ciproxin , Ciprobay
Treat infections of the urinary tract , prostate gland due to bacterial infection , pneumonia , diarrhea caused by bacteria , mikroplasma infections , gonorrhea ( gonorrhea )
Nausea ( rarely ) , permanent damage to the central nervous system ( rare ) , tendinosis ( chronic tendon damage or injury ) ( rare )
Inhibiting the enzyme DNA gyrase or topoisomerase IV thereby inhibiting DNA replication and transcription .
enoxacin
Penetrex
gatifloxacin
Tequin
levofloxacin
Levaquin
Lomefloxacin
Maxaquin
moxifloxacin
Avelox
Nalidixic acid
NegGram
norfloxacin
Noroxin
ofloxacin
Floxin , Ocuflox
Trovafloxacin
Trovan
Circulation of this antibiotic is discontinued
Grepafloxacin
Raxar
Circulation of this antibiotic is discontinued
sparfloxacin
Zagam
Circulation of this antibiotic is discontinued
Temafloxacin
Omniflox
Circulation of this antibiotic is discontinued
20 . sulfonamide
Mafenide
Sulfamylon
Nfeksi overcome urinary tract ( except sulfacetamida which , used for eye infections , and mafenide and Silver sulfadiazine , which is used for burns with topically )
Nausea , vomiting , and diarrhea .
Allergies ( including skin rashes )
Crystals in the urine .
renal failure
Decrease in the number of white blood cells .
Sensitive to sunlight
Inhibit the synthesis of folate . This antibiotic is a competitive inhibitor for the enzyme dihydropteroate synthetase , DHPS . DHPS , in which the enzyme is a catalyst that converts PABA ( para- aminobenzoate ) to dihydropteroate , but the conversion process is a key pathway for the synthesis of folate . Folate is necessary for the cell to synthesize nucleic acids ( nucleic acids is an important builder compounds for DNA and RNA ) . The absence of folate will mengkibatkan cells can not do division .
sulfacetamide
Sulamyd , Bleph - 10
sulfadiazine
Micro - sulfone
Silver sulfadiazine
Silvadene
sulfadimethoxine
In - Methox , Albon
Sulfamethizole
Thiosulfil Forte
sulfamethoxazole
Gantanol
Sulfanilimide

sulfasalazine
Azulfidine
Sulfisoxazole
Gantrisin
Trimethoprim - Sulfamethoxazole ( Co - trimoxazole ) ( TMP - SMX )
Bactrim , Septra
Sulfonamidochrysoidine
Prontosil

21 . Tetracycline
demeclocycline
Declomycin
Overcoming Syphilis , chlamydia infections , Lyme disease , mycoplasma infection , infection rikettsia on acne , malaria . Note : Malaria is caused by protists , not by bacteria .
indigestion
Sensitive to sunlight
Potential toxicity ( poisoning ) in the mother and fetus during pregnancy
Enamel hypoplasia ( staining of the teeth , potentially permanent )
Temporary decline in bone growth .
Inhibits the binding of aminoacyl - tRNA to the mRNA - ribosome complex . This antibiotic also binds to the 30S ribosomal subunit mRNA translation .
doxycycline
Vibramycin
minocycline
Minocin
oxytetracycline
Terramycin
tetracycline
Sumycin , Achromycin V , Steclin
22 . Medicines against mycobacteria
clofazimine
Lamprene
Antileprostatik ( antikusta / leprosy )

dapsone
Avlosulfon
Antileprostatik ( antikusta / leprosy )

Capreomycin
Capastat
antituberculosis


cycloserine
Seromycin
Antituberculosis , overcome urinary tract infections

ethambutol
Myambutol
antituberculosis

Ethionamide
Trecator
antituberculosis

Inhibit the synthesis of peptides
isoniazid
I.N.H.
antituberculosis


Pyrazinamide
Aldinamide
antituberculosis


Rifampicin ( Rifampin in the U.S. )
Rifadin , Rimactane
Treat infections caused by gram-negative bacteria and mycobacteria
Sweat , tears and urine to be orange .
Binding β subunit of RNA polymerase thus inhibiting transcription .
rifabutin
Mycobutin
Cope with Mycobacterium avium complex ( MAC ) is a group of genetically related bacterial genus Mycobacterium .
rash , urine , symptoms of gastrointestinal ( GI ) such as abdominal pain , heartburn , diarrhea , constipation , nausea and vomiting .

Rifapentine
Priftin
antituberculosis


streptomycin

antituberculosis
Neurotoxicity ( state exposure to neurotoxins , which are substances , conditions or circumstances that damages the nervous system and / or brain , usually by killing neurons .
Ototoxicity ( damage to the ear ( oto - ) , specifically the cochlea or auditory nerve and sometimes the vestibular system due to toxic or antibiotics )
Aminogloserida similar mechanism of action .
23 . Other classes
Arsphenamine
Salvarsan
Spirochaetes tackle infections
Very Rare: aplastic anemia ( a disease in which the bone marrow and blood stem cells that exist in the inside were damaged . Thing It causes three types of blood cell deficiency ( pancytopenia ) as lack of red blood cells ( anemia ) , white blood cells ( leukopenia ) , and platelets ( thrombocytopenia ) . Aplastic refers to the inability of stem cells to produce mature blood cells .
Inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome
chloramphenicol
Chloromycetin
Tackle meningitis , or topical agents for the treatment of cheap . Formerly used to treat typhoid fever , cholera , gram-negative bacteria , gram-positive , and anaerobic

Fosfomycin
Monurol
Cystitis ( bladder infection ) acute in women .

Disabling enolpyruvyl transferase , thereby blocking cell wall synthesis .
acid fusidik
Fucidin

metronidazole
Flagyl
Infections caused by anaerobic bacteria , amoebiasis ( infection caused by the amoeba Entamoeba histolytica ) , trichomoniasis ( inflammation in the vag * na due protozoan parasite , Trichomonas vaginalis , giardiasis ( beaver fever ) is a disease caused by the protozoan parasite Giardia lamblia berflagella or also called Giardia intestinalis and Giardia duodenal
Discolored urine , headache , metallic taste in the tongue , nausea ( alcohol is contraindicated )
Produces toxic free radicals that interfere with the activity of DNA and protein . Non-specific mechanism is closely related to its activity against a variety of bacteria , amoebae , and protozoa .
mupirocin
Bactroban
Ointment for impetigo ( skin infection that is very contagious , usually affects children who have not entered the school ) , cream for infected wounds

Platensimycin

Quinupristin / dalfopristin
Synercid

Thiamphenicol

Overcoming the Gram negative bacteria , Gram-positive , and anaerobic . Antibiotics are widely used in veterinary medicine .

This is an analog of antibiotic compounds ( similar to both the structure and function ) of chloramphenicol . This antibiotic inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome
tigecycline
Tigacyl
Cope with complex skin infections ( infections of skin and associated tissues ) , intra- abdominal infection ( infection of the peritoneum or retroperitoneal ) , and discoloration of the teeth .
rash

tinidazole
Tindamax Fasigyn
Treat infections caused by protozoa .
abdominal pain , bitter taste , and itching

trimethoprim
Proloprim , Trimpex
Overcoming urinary tract infection

You now know the classification of Antibiotics , Antibiotic Types or Kinds of Antibiotics . Thank you you 've been to the Cyber ​​Library .

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